11:12 AM EDT, 05/30/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were relatively flat Friday morning, edging 0.01% lower to 1,453.06 on the S&P Europe Select ADR Index, which ended the week up 1.4% and closed out the month nearly 4% higher.

From continental Europe, the gainers were led by accommodations booking company trivago (TRVG) and software firm SAP (SAP), which rose 2.4% and 1.7% respectively. They were followed by pharmaceutical company Novo Nordisk ( NVO ) and biopharmaceutical company Genfit ( GNFT ) , which were up 1.2% and 0.9% respectively.

The decliners from continental Europe were led by pharmaceutical company Sanofi ( SNY ) and biotech firm BioNTech (BNTX), which fell 5.1% and 4.9% respectively. They were followed by telecommunications company Nokia ( NOK ) and semiconductor company Sequans Communications ( SQNS ) , which lost 2.3% and 2.2% respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical company Verona Pharma ( VRNA ) and pharmaceutical company GSK (GSK), which increased 2.6% and 2.3% respectively. They were followed by biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and utilities company National Grid ( NGG ) , which advanced 1.9% and 1% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Bicycle Therapeutics ( BCYC ) and NuCana ( NCNA ) , which dropped 3.8% and 3% respectively. They were followed by biopharmaceutical company Mereo BioPharma Group ( MREO ) and biotech firm Autolus Therapeutics ( AUTL ) , which were down 2.9% and 2.3% respectively.