09:04 AM EST, 12/20/2024 (MT Newswires) -- Health care stocks were mixed premarket Friday, with The Health Care Select Sector SPDR Fund ( XLV ) up 0.8% and the iShares Biotechnology ETF (IBB) 0.4% lower.

Novo Nordisk ( NVO ) shares were down past 21% in recent Friday premarket activity, recovering from a 40% fall earlier, after the company said its experimental obesity therapy, CagriSema, met the primary endpoint in a phase 3 trial, showing superior weight loss compared with placebo, but the results fell short of its expectations.

Hims & Hers Health ( HIMS ) stock was more than 1% lower after closing down 7.7% on Thursday following a US Food and Drug Administration determination that a shortage of Eli Lilly's ( LLY ) popular weight loss drug tirzepatide has ended.

Ionis Pharmaceuticals ( IONS ) shares were nearly 4% higher after the company said the US Food and Drug Administration has approved Tryngolza as an adjunct to diet to reduce triglycerides in adults with familial chylomicronemia syndrome.