12:00 PM EDT, 05/13/2025 (MT Newswires) -- The European stock markets closed mixed in Tuesday trading as The Stoxx Europe 600 was up 0.07%, Germany's DAX gained 0.23%, the FTSE 100 was off 0.02% , France's CAC 40 rose 0.30%, and the Swiss Market Index declined 0.44%.

The industrial downturn in Europe is cooling, according to procurement and supply chain consultant GEP, which publishes the Global Supply Chain Volatility Index. The firm said supply chain capacity was underused at its smallest rate in 10 months, indicating growth in Germany and France. However, it also said the UK continued to register "significant manufacturing weakness," as supplier activity is down at a rate that "has rarely been surpassed in 20 years of data availability."

In Germany, the ZEW Indicator of Economic Sentiment in the country rebounded in May to 25.2 points, which is 39.2 points higher than in April. "Expectations are brightening," ZEW President Achim Wambach said in a statement. "With a new government in place, some progress in the tariff disputes and a stabilizing inflation rate, optimism has increased."

And in corporate news, shares of Bayer rose 2.8% in Frankfurt after the German chemicals company reported Q1 core earnings that fell year-over-year but beat analyst expectations.

Irish airline Ryanair said Tuesday it was informed of a security threat on a flight from Faro, Portugal to Brussels South Charleroi airport in Belgium. Portugal's official LUSA news agency described a fake bomb threat on board the plane.

Shares of Ryanair were down 0.8% on the Euronext Dublin exchange.

British pharmaceutical company GSK and iTeos Therapeutics said Tuesday they are ending the development program for belrestotug as two phase 2 cancer studies failed to meet the efficacy criteria for continued development. The companies said that as a result, they are ending their collaboration and all belrestotug-containing study groups.

Shares of GSK were down 3% in London trading.