11:06 AM EDT, 10/21/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were down late Tuesday morning, declining 0.2% to 1,586.32 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by telecommunications company Ericsson (ERIC) and pharmaceutical company Sanofi ( SNY ), which rose 1.3% and 0.6% respectively. They were followed by petroleum refiner Equinor ( EQNR ) and accommodations booking site trivago (TRVG), which were up 0.4% and 0.3% respectively.

The decliners from continental Europe were led by biopharmaceutical company Cellectis ( CLLS ) and biotech firm Evaxion ( EVAX ) , which fell 7% and 6% respectively. They were followed by semiconductor company Sequans Communications ( SQNS ) and pharmaceutical company Ascendis Pharma ( ASND ) , which were down 3.5% and 3.3% respectively.

From the UK and Ireland, the gainers were led by software firm Endava ( DAVA ) and cruise line operator Carnival (CUK), which advanced 4.3% and 2.4% respectively. They were followed by educational publisher Pearson (PSO) and lender HSBC ( HSBC ) , which increased 1.6% and 1.4% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Adaptimmune Therapeutics ( ADAP ) and NuCana ( NCNA ) , which tumbled 22% and 10% respectively. They were followed by biotech firms Autolus Therapeutics ( AUTL ) and Trinity Biotech ( TRIB ) , which dropped more than 4% and 3% respectively.