10:58 AM EDT, 09/24/2025 (MT Newswires) -- European equities traded in the US as American depositary receipts were little changed Wednesday morning, edging 0.11% higher to 1,557.25 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by petroleum refiner Equinor ( EQNR ) and software firm SAP (SAP), which rose 2.4% and 2.3%, respectively. They were followed by oil and gas company TotalEnergies (TTE) and internet advertising firm Criteo ( CRTO ) , which were up 2.1% and 1.6%, respectively.

The decliners from continental Europe were led by semiconductor company Sequans Communications ( SQNS ) and telecommunications company Nokia ( NOK ) , which dropped 3.3% and 2.2%, respectively. They were followed by telecommunications company Ericsson (ERIC) and pharmaceutical company Novo Nordisk ( NVO ) , which lost 1.6% each.

From the UK and Ireland, the gainers were led by biopharmaceutical companies Akari Therapeutics ( AKTX ) and Bicycle Therapeutics ( BCYC ) , which advanced 13% and 5.4%, respectively. They were followed by biotech firm Autolus Therapeutics ( AUTL ) and biopharmaceutical company Mereo BioPharma Group ( MREO ) , which increased 2.2% and 1.9%, respectively.

The decliners from the UK and Ireland were led by biopharmaceutical company Adaptimmune Therapeutics ( ADAP ) and British American Tobacco ( BTI ) , which fell 8.9% and 1.7%, respectively. They were followed by alcoholic beverage company Diageo ( DEO ) and pharmaceutical company GSK (GSK), which were off 0.7% and 0.6%, respectively.