07:03 AM EST, 02/12/2025 (MT Newswires) -- The main US stock measures were pointing lower in Wednesday's premarket activity as traders await a key inflation report.

Standard & Poor's 500 edged down 0.1%, the Dow Jones Industrial Average declined 0.2% while the Nasdaq was slightly in the red before the opening bell. The majority of Asian and European exchanges were trending higher.

The consumer price index report for January is scheduled for an 8:30 am ET release. Government data are expected to show Wednesday that consumer inflation rose 0.3% sequentially last month in the US, according to a Bloomberg-compiled consensus.

Also on Wednesday's economic calendar, the weekly mortgage applications bulletin posts at 7 am, followed by the weekly EIA petroleum inventories report at 10:30 am.

Federal Reserve Chair Jerome Powell is scheduled to speak before the House Financial Services Committee at 10 am. Atlanta Fed President Raphael Bostic speaks at 12 pm, while Fed Governor Christopher Waller is slated to speak at 5:05 pm.

Shares of DoorDash ( DASH ) rose 6.6% pre-bell as the food delivery company topped Wall Street's expectations for revenue in the fourth quarter. Lyft ( LYFT ) dropped 13% as the ride-hailing company issued a downbeat first-quarter outlook for gross bookings. Upstart (UPST) jumped 28% as the artificial intelligence lending platform posted upbeat quarterly results.

CME Group ( CME ) , CVS Health ( CVS ) , Dominion Energy ( D ) , Kraft Heinz ( KHC ) , Restaurant Brands International (QSR), Biogen (BIIB) and Lithia Motors ( LAD ) report their latest financial results before the bell, among others. Cisco Systems ( CSCO ) , Trade Desk ( TTD ) , Robinhood Markets ( HOOD ) and Reddit ( RDDT ) post earnings after markets close.

In premarket action, bitcoin increased 1.2% to $96,293, West Texas Intermediate crude oil fell 1.2% to $72.44 per barrel, yields on 10-year Treasuries inched 0.2 basis points higher to 4.54% and gold moved down 0.8% to $2,910 an ounce.