April 29 (Reuters) - AbbVie ( ABBV ) on Wednesday reported better-than-expected quarterly revenue and profit, fueled by demand for newer immunology drugs Skyrizi and Rinvoq, as the drugmaker continues to navigate its transition away from its once-blockbuster drug, Humira.

The company has been leaning heavily on Skyrizi and Rinvoq to fill the void left by Humira, which lost U.S. patent exclusivity in 2023 and has since faced a wave of cheaper biosimilar competition.

Last year, AbbVie ( ABBV ) said it expects the two drugs to bring in more than $31 billion in combined sales by 2027.

Skyrizi recorded sales of $4.48 billion for the first quarter, growing 30.9% from a year earlier and beating Wall Street estimates of $4.41 billion, according to LSEG data. Rinvoq sales grew 23.3% to $2.12 billion, also topping estimates of $2.04 billion.

Global sales of Humira fell 38.6% to $688 million in the quarter, slightly missing analysts' expectation of $696.5 million.

In January, the drugmaker struck a deal with the Trump administration to lower prices of certain medications including Humira, providing the company with an exemption from tariffs and future pricing mandates.

Beyond immunology, AbbVie's ( ABBV ) neuroscience portfolio emerged as a standout performer, with revenue surging 26% to $2.88 billion. Its Global Botox Therapeutic crossed the $1 billion quarterly mark for the first time, which was also ahead of expectations of $996.5 million.

On an adjusted basis, the company earned $2.65 per share for the quarter ended March 31, above analysts' expectations of $2.59 per share.

Quarterly revenue came in at $15 billion, compared to analysts' estimate of $14.72 billion.

AbbVie ( ABBV ) also raised its full-year adjusted earnings forecast to a range of $14.08 to $14.28 per share from $13.96 to $14.16. The forecast includes a 41 cent per share hit from acquired in-process R&D and milestone expenses booked through the first quarter.