By Puyaan Singh
Sept 4 (Reuters) - Amgen ( AMGN ) will test its obesity
drug candidate in patients at risk of weight-related conditions
such as heart, liver and kidney diseases in its late-stage
trial, the company's CEO Robert Bradway said on Wednesday.
Speaking at a Morgan Stanley healthcare conference, Bradway
described MariTide as a next-generation obesity drug due to its
different mechanism of action and less frequent dosing compared
to Eli Lilly's ( LLY ) Zepbound and Novo Nordisk's
Wegovy, which require weekly-dosing.
"Our medicine is likely to be administered monthly or less
frequently than that, so that means we're giving a quarter of
the number of injections as the two competitors that are on the
market now, each month," he said.
Lilly and Novo have been struggling to produce enough of
their obesity medications to meet the soaring demand, though
Lilly ramped up its manufacturing in the last quarter.
"Some of their supply challenge is a function of the number
of injections they're having to provide. We start with the
benefit of doing a quarter of what they're looking to do,"
Bradway said.
The company had said in August it expects to have initial
data from a mid-stage trial of MariTide late this year.