Sept 17 (Reuters) - Drug developer Arvinas ( ARVN ) said
on Wednesday it will grant commercialization rights of an
experimental breast cancer treatment it was developing with
Pfizer ( PFE ) to a third party.
Shares of Arvinas ( ARVN ) were down 3.4% in extended trading.
The drug vepdegestrant is currently under review by the U.S.
Food and Drug Administration for a type of breast cancer, and
the regulator will give its potential approval decision in June.
Arvinas ( ARVN ) said it will limit additional expenditures on
vepdegestrant to support activities required for making the drug
ready for commercialization.
"The companies are aligned in their belief that finding a
third-party commercial partner is the best path forward ... and
ensure vepdegestrant is available promptly if approved for use
by regulatory authorities," said Arvinas ( ARVN ).
It will also reduce its workforce by an additional 15%,
"with the most significant reductions being roles related to
vepdegestrant commercialization". Arvinas ( ARVN ) had previously
announced a 33% workforce reduction in May.
The company had 430 full-time employees as of December 31,
2024, according to its latest annual filing.
Arvinas ( ARVN ) said the out-licensing of vepdegestrant and the
resulting cost-cutting actions are expected to result in overall
annual cost savings of more than $100 million compared with
2024, when combined with the $80 million it announced in May.
The drug developer said the cost cuts along with a new stock
buyback program of up to $100 million were "actions to support
shareholder value creation".
In May, trial results showed vepdegestrant delayed
progression of breast cancer by more than three months compared
to AstraZeneca's ( AZN ) Faslodex in patients with a specific
gene mutation.