April 25 (Reuters) - Cigna ( CI ) plans to make close
copies of AbbVie's ( ABBV ) blockbuster arthritis drug Humira
available with no out-of-pocket payment to eligible patients in
the U.S. using its specialty pharmacy beginning in June, the
health insurer said on Thursday.
Cigna ( CI ) said it will stock high- and low-concentration
biosimilar versions of Humira from drugmakers including
Boehringer Ingelheim, Teva and Alvotech ( ALVO ) at
its Accredo pharmacy.
"Not all biosimilars are created equal," Matt Perlberg,
president of Cigna's ( CI ) Evernorth Health Services' pharmacy and
care delivery businesses, said in an interview. "We know that
patients need options, and we wanted to make sure that we offer
the right experience, level of clinical care, and affordability
for as many eligible patients as possible."
Unlike easy to manufacture pills that can be copied and sold
as generics at a huge discount once patents lapse, complex
biologic medicines made from living cells cannot be exactly
duplicated. Their close alternatives are called biosimilars.
Despite nine biosimilars being launched in the U.S. last
year, AbbVie ( ABBV ) has held onto more than 98% of the Humira market.
Privately-held German drugmaker Boehringer launched its version,
Cyltezo, last July but has only managed to sell a couple
thousand prescriptions in total since then, according to IQVIA
data.
Almost 3 million Humira prescriptions have been written
during the same period, although tens of thousands of scripts
have started to shift to biosimilar Hyrimoz each week since CVS
Health's ( CVS ) pharmacy benefits unit took Humira off the list
of drugs it recommends insurers reimburse. Hyrimoz is made by
Switzerland's Sandoz.
Cyltezo and Simlandi, from Israel's Teva and Iceland's
Alvotech ( ALVO ), are designated as interchangeable, meaning they can be
substituted for the original without consulting the prescriber.
Simlandi, which was approved in the U.S. in February, is the
only interchangeable biosimilar of Humira that also comes in a
high-concentration dose.
AbbVie's ( ABBV ) high-concentration version of Humira makes up close
to 90% of its sales in the United States.
Cigna ( CI ) said these biosimilars will be priced at about 85%
lower than the $6,922.62 monthly list price of Humira, and that
it had made agreements with the manufacturers as well as its
distributor Quallent to bring the out-of-pocket cost down to $0.
The company said the move should save around $3,500 on
average per year for some of the 100,000 Accredo patients
currently using either Humira or one of its biosimilars.
Perlberg did not provide an estimate for how many patients they
anticipate switching.
"Different patients adopt products at different times," said
Perlberg.