Oct 6 (Reuters) - MapLight is aiming to raise up to

$250.8 million in an initial public offering in the U.S., the

biopharmaceutical company said on Monday.

U.S. IPO activity has picked up in recent months,

reversing a slowdown earlier in the year when trade-policy

uncertainty curbed momentum, as recent listings have attracted

strong investor demand.

MapLight will list on the Nasdaq under the symbol

"MPLT."

Morgan Stanley, Jefferies, Leerink Partners and Stifel

are the underwriters for the offering.