Oct 24 (Reuters) - Eli Lilly ( LLY ) announced on Friday
safety and efficacy results from two separate late-stage studies
testing its approved drugs for alopecia and eczema.
The company was testing baricitinib, sold under the brand
name Olumiant, in 257 adolescent patients with severe alopecia
areata or patchy hair loss. In the trial, a 4 milligram dose of
baricitinib helped improve hair regrowth in more than 50% of
adolescents after one year of treatment.
Successful regrowth was also observed with a 2 milligram
dose, the company said, adding that the safety profile of
baricitinib remained consistent with previous reports.
In another trial, Lilly was testing Ebglyss, chemically
known as lebrikizumab, in 103 patients with moderate-to-severe
atopic dermatitis, a chronic skin condition commonly known as
eczema.
The company said lebrikizumab dosed every eight or four
weeks provided long-lasting response.
Lilly said it has submitted the data from the studies to the
U.S. Food and Drug Administration for a potential label update.
Ebglyss is an approved injectable medicine used to treat
adults and children 12 years and older with moderate-to-severe
eczema who cannot use topical therapies.
Olumiant is approved to treat adults with severe alopecia
areata and adults with moderately to severely active rheumatoid
arthritis, if prior treatment did not work.