April 25 (Reuters) - Gilead Sciences ( GILD ) reported a

first-quarter loss on Thursday after taking a $3.9 billion

charge for its recent acquisition of liver drug developer

CymaBay Therapeutics, while revenue rose 5% on higher HIV,

oncology and liver disease treatment sales.

For full-year 2024, Gilead said it still expects product

sales of $27.1 billion to $27.5 billion, but lowered its

earnings outlook to include the recent charge as well as

incremental expenses related to the CymaBay deal.

The company said it now expects 2024 adjusted profit of

$3.45 to $3.85 a share, down from a previous range of $6.85 to

$7.25.

"This is mostly expected and hence no major surprises,"

Jefferies analyst Michael Yee said in a research note.

Wall Street analysts currently project Gilead's 2024

earnings at $3.94 a share on revenue of $27.5 billion, according

to LSEG data.

Shares of Gilead, which fell 2.7% to close at $65.27 on

Thursday, were up 3.3% at $67.44 in after hours trading.

The California-based drugmaker's first-quarter revenue

totaled $6.69 billion, ahead of the average analyst projection

of $6.34 billion.

Gilead posted an adjusted quarterly loss of $1.32 a share,

which was better than the $1.48 per share loss forecast by

analysts.

On a net basis, which included a $2.4 billion writedown of

assets acquired from Immunomedics in 2020, Gilead reported a

quarterly loss of $3.34 per share.

HIV product sales increased 4% from a year earlier to $4.3

billion. Quarterly sales of HIV drug Biktarvy rose 10% to $2.9

billion, which was in line with analyst estimates.

Gilead's oncology sales rose 18% to $789 million.

"We had a really strong quarter as reflected in both our

commercial performance and clinical execution," Gilead CEO

Daniel O'Day said in an interview.

He added that Gilead has "54 active clinical programs and no

major patent expiries until the end of 2030."

The company expects pivotal-stage trial results later this

year from several key programs, including cancer drug Trodelvy

and a long-acting HIV prevention drug.

The U.S. Food and Drug Administration is slated to decide by

Aug. 14 whether to approve seladelpar, an experimental treatment

for a rare liver disease developed by CymaBay.