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Immutep Says its Mid-Stage Trial of Eftilagimod Alfa Meets Primary Endpoint of Tumor Hyalinization/Fibrosis
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Immutep Says its Mid-Stage Trial of Eftilagimod Alfa Meets Primary Endpoint of Tumor Hyalinization/Fibrosis
Oct 20, 2025 6:42 AM

09:20 AM EDT, 10/20/2025 (MT Newswires) -- Immutep ( IMMP ) said Monday that its Eftisarc-neo mid-stage study of eftilagimod alfa with radiotherapy plus Keytruda has met its primary endpoint and "significantly exceeded" the trial's prespecified 35% tumor hyalinization/fibrosis.

The company said the trial enrolled 38 participants and found that the novel combination with eftilagimod alfa resulted in a median 51.5% tumor hyalinization/fibrosis in patients with soft tissue sarcoma.

The trial showed a "very good safety profile" for the therapy, with results obtained across multiple soft tissue sarcoma subtypes, the company said.

Shares of the company were down 1.9% in recent Monday premarket activity.

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