By Rishika Sadam
HYDERABAD, April 18 (Reuters) - Indian drugmaker Biocon
, looking to grab a piece of the exploding weight-loss
drug market as early as possible, is developing its own version
of Novo Nordisk's wildly popular Wegovy and is
prepared to conduct a clinical trial next year if needed, the
CEO told Reuters.
Wall Street has forecast the market for this new generation
of obesity treatments reaching at least $100 billion by the end
of the decade, and Biocon is taking steps to be a part of that
windfall.
"We're going to develop semaglutide for India even if it
requires a clinical trial," Chief Executive Officer Siddharth
Mittal said in an interview of the active ingredient in Wegovy
and Ozempic. "We're striving to be in the market as one of the
early players. Either it would be in 2026 or not too late after
that."
The Bengaluru-based company, which derives most of its
revenue from foreign markets such as the United States, also
aims to first launch generic versions of the weight-loss drugs
in other emerging markets such as Brazil, Mexico, and Saudi
Arabia.
Semaglutide will lose patent protection in those countries
in 2026, Mittal said, adding that the company is talking to
local manufacturers regarding partnerships to ensure supply.
Novo did not immediately respond to a request for comment on
patent expirations in the respective countries.
Biocon will first try to get a waiver on clinical trials
from Indian regulators and instead submit bioequivalence studies
showing that their version has an equivalent effect as
semaglutide, Mittal said.
The company is also developing a version of tirzepatide, the
active ingredient in Eli Lilly's ( LLY ) rival obesity treatment
Mounjaro and Zepbound, Mittal said, without providing details on
the timing or initial marketing strategy.
Both Novo and Lilly have so far been unable to keep up with
seemingly insatiable demand for their obesity treatments.
Biocon has been spending roughly 2.5 billion rupees ($30
million) a year on generics research and development with 40%
dedicated to developing peptides including for the weight-loss
drugs.
Biocon will likely face competition from Indian rivals such
as Dr Reddy's and Cipla, which are aiming to
bring their own versions of Wegovy to India, subject to patent
expiries.
Novo has so far launched Wegovy in a few wealthy countries,
but said it aims to bring the drug to India by 2026.
Lilly diabetes treatment Mounjaro is under review by India's
drug regulators for weight loss. It was approved for weight loss
in Europe under the same brand name but is sold in the United
States for obesity as Zepbound.
Wegovy helped patients in clinical trials lose an average of
15% of their body weight, while Mounjaro led to an average loss
of 18%. The medicines belong to a class of therapies known as
GLP-1 receptor agonists which help control blood sugar and slow
digestion, helping people feel full longer.
Biocon has received UK approval for its version of Novo's
Saxenda, an earlier generation GLP-1 diabetes drug that also
helped people lose about 5% of their body weight. It has also
submitted the therapy for approval in Europe and India, Mittal
said.
($1 = 83.5310 Indian rupees)