08:27 AM EDT, 04/30/2025 (MT Newswires) -- Ionis Pharmaceuticals ( IONS ) reported a Q1 net loss Wednesday of $0.93 per diluted share, narrowing from a loss of $0.98 a year earlier.

Analysts polled by FactSet expected a loss of $1.10.

Revenue for the quarter ended March 31 was $132 million, up from $119 million a year earlier.

Analysts surveyed by FactSet expected $131.4 million.

The California life sciences company said it has lifted its 2025 revenue outlook to between $725 million to $750 million, up from its previous guidance of over $600 million. Analysts polled by FactSet expect $643.0 million.

Shares of the company were up more than 3.5% in recent premarket activity.