07:43 AM EST, 02/19/2025 (MT Newswires) -- Ionis Pharmaceuticals ( IONS ) reported a Q4 net loss Wednesday of $0.66 per diluted share, widening from a loss of $0.06 a year earlier.

Analysts polled by FactSet expected a loss of $1.11.

Revenue for the quarter ended Dec. 31 was $227 million, down from $325 million a year earlier.

Analysts surveyed by FactSet expected $135.3 million.

For the full year, the company said it expects revenue of more than $600 million.

Analysts polled by FactSet expect $666.2 million.