June 10 (Reuters) - A woman who claimed in a lawsuit
that GSK's discontinued heartburn drug Zantac caused her
breast cancer dropped her case shortly before it was set to go
to trial in Illinois state court on Monday, the company
announced.
GSK said in a statement that it did not settle with the
woman, Eugenia Kasza. A lawyer for Kasza did not immediately
respond to a request for comment.
Kasza's case would have been the second over Zantac to go to
trial, after the first ended last month with a victory for GSK
and Boehringer Ingelheim, which also sold Zantac. Another case
was dismissed by a judge shortly before a trial was set to begin
on May 23.
More than 72,000 lawsuits remain pending over Zantac against
companies that sold the drug, which also include Pfizer ( PFE )
and Sanofi. Sanofi has settled about 4,000 cases, and
the Financial Times reported last month that Pfizer ( PFE ) had settled
more than 10,000 cases.
A Delaware judge earlier this month ruled that the cases
could go forward, rejecting a bid by GSK and other drugmakers to
stop plaintiffs from offering expert testimony that the drug can
cause cancer. The drugmakers have said they will appeal.
First approved in 1983, Zantac became the world's best
selling medicine in 1988 and one of the first to top $1 billion
in annual sales. It was originally marketed by a forerunner of
GSK and later sold successively to other companies.
In 2019, some manufacturers and pharmacies halted Zantac
sales after a chemical called NDMA, which is known to cause
cancer, was detected in some pills. Some tests showed that
Zantac's active ingredient, ranitidine, could degrade into NDMA
over time or when exposed to heat.
The U.S. Food and Drug Administration asked manufacturers to
pull the drug off the market in 2020. In the face of mounting
lawsuits, the drugmakers have maintained that there is no
evidence Zantac exposed users to harmful levels of NDMA.
The companies notched a significant win in 2022, when
another judge rejected about 50,000 lawsuits making similar
claims that had been consolidated in federal court in Florida.
Some plaintiffs are appealing that ruling.