Oct 15 (Reuters) - Eli Lilly ( LLY ) said on Wednesday
its experimental pill, orforglipron, helped reduce blood sugar
levels in two late-stage trials.
The oral drug is designed to mimic the appetite-suppressing
GLP-1 hormone targeted by the company's blockbuster injection
tirzepatide, sold under the brand names Mounjaro and Zepbound.
In one of the studies, Lilly's pill helped lower A1C, a
measure of blood sugar over time, by up to 1.7% compared to 0.8%
with AstraZeneca's ( AZN ) drug dapagliflozin. The head-to-head
trial was conducted in adults with type 2 diabetes inadequately
controlled on metformin, a widely used to drug used to treat
high blood sugar levels.
In the other trial, orforglipron lowered A1C by an
additional 2.1% when taken with insulin glargine.