financetom
Business
financetom
/
Business
/
Moderna Shares Fall After Early Trial Update on mRNA-4359 Cancer Vaccine Combination
News World Market Environment Technology Personal Finance Politics Retail Business Economy Cryptocurrency Forex Stocks Market Commodities
Moderna Shares Fall After Early Trial Update on mRNA-4359 Cancer Vaccine Combination
Oct 17, 2025 1:01 PM

03:32 PM EDT, 10/17/2025 (MT Newswires) -- Moderna ( MRNA ) shares were down almost 5% in recent trading on Friday after management provided an update on the company's immunotherapy pipeline and presented trial data evaluating its mRNA-4359 cancer vaccine together with pembrolizumab, according to a FactSet transcript of Moderna's ( MRNA ) oncology investor event.

The company said Monday that mRNA-4359 in combination with pembrolizumab showed "promising" results in its phase 1/2 trial in certain melanoma patients and that it continues to study mRNA-4359 in the phase 2 portion of the ongoing phase 1/2 trial, both as a standalone therapy and in combination with pembrolizumab in patients with advanced melanoma and non-small cell lung cancer.

Moderna ( MRNA ) expects five-year follow up data to "mature later this year," with data from the phase 2 study expected to be shared "at the end of the year or early in 2026," according to Friday's transcript.

The company is also expanding the study into additional cohorts and combination arms, the transcript said.

Price: 25.81, Change: -1.33, Percent Change: -4.90

Comments
Welcome to financetom comments! Please keep conversations courteous and on-topic. To fosterproductive and respectful conversations, you may see comments from our Community Managers.
Sign up to post
Sort by
Show More Comments
Related Articles >
Japan's Seven & i set to announce new CEO and restructuring plan, say sources
Japan's Seven & i set to announce new CEO and restructuring plan, say sources
Mar 5, 2025
* Stephen Dacus likely to become new CEO, first foreign leader * Seven & i ( SVNDF ) to sell non-core assets to Bain Capital, says report * Plans to announce share buyback of about $13.4 billion, says report * Another report said earlier this week Couche-Tard's $47 billion bid will be rejected (Adds report of share buyback, share move,...
Volkswagen's entry-level electric car targeted at Europe, brand chief says
Volkswagen's entry-level electric car targeted at Europe, brand chief says
Mar 5, 2025
DUESSELDORF, March 5 (Reuters) - Volkswagen will focus the sales strategy for its 20,000-euro ($21,580.00) electric car coming out in 2027 on Europe, its brand chief said on Wednesday, adding the carmaker needed until then to bring down battery costs to sell it at that price. The car will be the first in Volkswagen's line-up to feature software from its...
BRIEF-Seven & I Plans To List North American Convenience Store Subsidiary In Or After 2026, Nikkei Says
BRIEF-Seven & I Plans To List North American Convenience Store Subsidiary In Or After 2026, Nikkei Says
Mar 5, 2025
March 6 (Reuters) - SEVEN & I PLANS TO LIST NORTH AMERICAN CONVENIENCE STORE SUBSIDIARY IN OR AFTER 2026, NIKKEI SAYS Further company coverage: (Reporting by Tokyo Newsroom) ...
Singapore adds charges for two held in server fraud case
Singapore adds charges for two held in server fraud case
Mar 5, 2025
SINGAPORE, March 6 - Singapore authorities added fresh charges on Thursday against three men charged with server fraud, court documents showed, in a case that has drawn international attention for possible infringement of export controls. The case is part of a wider police investigation of 22 individuals and companies suspected of false representation, amid concerns that organised AI chip smuggling...
Copyright 2023-2026 - www.financetom.com All Rights Reserved