LONDON, Aug 14 (Reuters) - Vaccines to help curb an
escalating mpox outbreak in Democratic Republic of Congo and
neighbouring countries may still not reach the central African
country for months even as the World Health Organization
considers following Africa's top public health agency in
declaring the outbreak an emergency.
On Tuesday, Africa Centres for Disease Control and
Prevention declared a public health emergency of continental
concern for the first time ever, and on Wednesday, a WHO-led
panel meets to decide if it represents a global threat.
But while experts hoped the meetings would galvanise action
worldwide, many obstacles remain, including limited vaccine
supply, funding and competing disease outbreaks.
"It is important to declare an emergency because the disease
is spreading," said Jean-Jacques Muyembe-Tamfum, head of Congo's
Institut National pour la Recherche Biomedicale (INRB). He said
he hoped any declaration would help provide more funding for
surveillance as well as supporting access to vaccines in Congo.
But he acknowledged the road ahead was not easy in a huge
country where health facilities and humanitarian funds are
already stretched by conflict and outbreaks of diseases like
measles and cholera.
"If the big declarations remain just words, it won't make
any material difference," said Emmanuel Nakoune, an mpox expert
at the Institut Pasteur de Bangui in Central African Republic.
Africa CDC said last week it had been granted $10.4 million
in emergency funding from the Africa Union for its mpox
response, and its director general Jean Kaseya said on Tuesday
there was a clear plan to secure 3 million doses of vaccine this
year, without elaborating further.
However, sources involved in planning a vaccination roll-out
in Congo said only 65,000 doses were likely to be available in
the short-term, and campaigns were unlikely to begin before
October at the earliest.
There have been more than 15,000 suspected cases of mpox in
Africa this year and 461 deaths, mainly among children in Congo,
according to Africa CDC. The viral infection is usually mild but
can kill, and causes flu-like symptoms and pus-filled lesions.
A new offshoot of the virus has caused outbreaks in refugee
camps in the east of Congo this year, and spread to Uganda,
Burundi, Rwanda and Kenya for the first time.
Ivory Coast and South Africa are also experiencing outbreaks
linked to a different strain of the virus, which spread globally
in 2022, largely among men who have sex with men. This outbreak
prompted WHO to declare a global emergency before ending it 10
months later.
Then, two vaccines were used - Bavarian Nordic's ( BVNKF ) Jynneos,
and LC16, made by KM Biologics. Outside clinical trials, neither
has ever been available in Congo or across Africa, where the
disease has been endemic for decades. Only LC16 is approved for
use in children.
Congo's regulators approved the use of the vaccines
domestically in June, but the government is yet to officially
request any from either the manufacturers or governments like
the United States looking to make donations through the global
vaccine group, Gavi.