COPENHAGEN, Nov 24 (Reuters) - Novo Nordisk
said on Monday an older oral version of its semaglutide drug
failed to meet its main goal in late-stage trials testing
whether the medicine can slow cognitive decline in Alzheimer's
patients.
The data is key for Novo because Alzheimer's disease would
be a large new market for GLP-1 medicines like semaglutide after
blockbuster success in the treatment of obesity and diabetes.
Alzheimer's patients currently have limited treatment options.
The drug being tested is Novo's Rybelsus, a pill currently
approved only for treatment of type 2 diabetes. Both Rybelsus
and Novo's blockbuster drugs Ozempic and Wegovy are based on the
same active ingredient, semaglutide, a GLP-1 medicine.
(Writing by Stine Jacobsen and Maggie Fick; Editing by Jan
Harvey, Terje Solsvik and Anna Ringstrom)