June 11 (Reuters) - Denmark's Novo Nordisk is
partnering with biotech company Deep Apple Therapeutics in a
deal worth up to $812 million to develop drugs for
cardiometabolic diseases, including obesity, the
California-based company said on Wednesday.
Deep Apple discovers drug candidates using its AI-based
platform that screens virtual libraries of billions of compounds
to cut drug discovery time, the company said.
Under the deal, Novo will receive exclusive global rights to
develop and commercialize so-called non-incretin oral therapies,
which belong to a different class of medicines than its popular
weight-loss and diabetes drugs Wegovy and Ozempic.
WHY IT'S IMPORTANT
Novo has been trying to strengthen its foothold in the potential
$150 billion weight-loss drug market through the development of
next-generation treatments as well as acquisitions and
partnerships.
In March, the company signed two licensing deals and gained
access to experimental obesity drugs from Lexicon
Pharmaceuticals ( LXRX ) and China-based United Laboratories
International ( ULIHF ).
CONTEXT
Novo in May ousted CEO Lars Fruergaard Jorgensen over concerns
the Danish company - a world leader in the lucrative weight-loss
drug market - was losing its first-mover advantage.
The company's shares have plunged since hitting a record
high in June last year as competition, particularly from U.S.
rival Eli Lilly ( LLY ), eats into its market share, while
Novo's pipeline of new drugs has failed to impress investors.
BY THE NUMBERS
As part of the license agreement with Novo, Deep Apple will be
eligible to receive up to $812 million in payments, as well as
potential royalties on sales of any products that emerge from
their collaboration.
(Reporting by Sneha S K in Bengaluru; Editing by Shinjini
Ganguli)