Sagimet Biosciences Inc. ( SGMT ) said on Wednesday that denifanstat met all primary and secondary endpoints in a Phase 3 trial for moderate to severe acne vulgaris. The trial was conducted by Sagimet’s license partner, Ascletis Bioscience Co. Ltd., in China. Denifanstat is a once-daily oral small-molecule fatty acid synthase (FASN) inhibitor being developed by Ascletis as ASC40 for acne...

* Crete PA's revenue exceeds $300 million with 20 firms acquired * Thrive partners with OpenAI for customized accounting tools * Venture capital targets traditional services for AI-driven growth By Krystal Hu June 4 - Crete Professionals Alliance, an accounting platform backed by Thrive Capital, plans to invest over $500 million to acquire U.S.-based accounting firms in the next two...

08:32 AM EDT, 06/04/2025 (MT Newswires) -- RTX (RTX) said Wednesday that its Raytheon unit has been awarded a $1.1 billion contract from the US Navy to produce AIM-9X Block II missiles. The company said the contract will boost annual production to 2,500 missiles. The AIM-9X is an infrared-guided short-range missile that can be used in both air-to-air and surface-to-air...

08:26 AM EDT, 06/04/2025 (MT Newswires) -- AECOM ( ACM ) said Wednesday it has been selected by the US Air Force Civil Engineer Center to provide architecture and engineering services through a multiple-award task order contract with a $1.5 billion ceiling. The contract includes restoration, conservation, planning and environmental quality maintenance for the Air Force and other federal agencies,...