Aug 12 (Reuters) - Pfizer ( PFE ) said on Monday its
respiratory syncytial virus (RSV) vaccine Abrysvo generated a
strong immune response in a late-stage study of four groups of
adults aged 18 and older with a compromised immune system.
A single 120 microgram dose of the vaccine generated strong
neutralizing antibodies against both subtypes of RSV, called
RSV-A and RSV-B, across all groups in the study, Pfizer ( PFE ) said.
Abrysvo was well-tolerated in the study and showed a safety
profile consistent with findings from other studies of the
vaccine, it added.
The drugmaker plans to submit the data to regulatory
agencies for review.
The study tested two doses of Abrysvo in 203 adults across
four groups - those with a type of lung cancer, end-stage kidney
disease, autoimmune inflammatory disorder, and solid organ
transplant recipients - all of whom have compromised immunity
and are at risk of developing severe RSV-associated disease.
Pfizer's ( PFE ) vaccine is currently approved for people aged 60
and older and for use in women during the middle of the third
trimester of pregnancy to protect their babies.
RSV typically causes cold-like symptoms but is also a
leading cause of pneumonia in toddlers and older adults, leading
to 177,000 hospitalizations and 14,000 deaths in the United
States annually.
(Reporting by Mariam Sunny in Bengaluru; Editing by Devika
Syamnath)