Feb 28 (Reuters) - Praxis Precision Medicines ( PRAX )
said on Friday an independent committee had recommended that its
tremor drug trial be stopped for futility, as the trial was
unlikely to meet the main goal.
Shares of the company fell 40% in premarket trading.
The Independent Data Monitoring Committee indicated that
some underlying assumptions of the statistical model might have
influenced this outcome and encouraged Praxis to explore
alternative analysis methods.
Praxis said it had decided to continue the trials to
completion given the advanced stage of patient enrollment and
the advice received from the committee.
The experimental drug, ulixacaltamide, is in late-stage
development for the treatment of essential tremor, a condition
that affects the nervous system and causes involuntary and
rhythmic shaking.
The company will explore different analysis methods for the
final dataset and expects to read out results in the third
quarter of 2025.