Dec 3 (Reuters) - Roivant will discontinue the
development of its drug for a rare lung disease after it failed
to show treatment benefits in patients in a mid-stage trial.
The company's unit, Kinevant Sciences, said on Tuesday its
once-monthly injectable drug, namilumab, failed to meet the main
and secondary goals in the study evaluating it in 107 patients
with chronic active pulmonary sarcoidosis for about 6 months.
The disease causes lumps of inflammatory cells to form in
the lungs and other organs, leading to tissue damage and organ
dysfunction.
Current treatments for the disease are corticosteroids and
other immunosuppressants that only suppress the symptoms, which
include shortness of breath, chest pain and persistent dry
cough.
"Unfortunately science is sometimes humbling, and we are
proud to have made the attempt," Roivant CEO Matt Gline said in
a statement.
Shares of Roivant fell 2.3% in premarket trading.
Sarcoidosis affects 150,000 to 200,000 people in the United
States per year, according to the American Lung Association.
Drug developer aTyr Pharma's ( ATYR ) efzofitimod is also
being tested for the treatment of pulmonary sarcoidosis and is
in late-stage development.
(Reporting by Christy Santhosh in Bengaluru; Editing by
Shinjini Ganguli)