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Werner and Sarr score for Spurs in win over Man City

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Van Nistlerooy brings smiles back for Man United

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Liverpool, Newcastle also reach League Cup quarters

(Adds quotes, quarter-final draw)

LONDON, Oct 30 (Reuters) - Tottenham Hotspur beat Manchester City 2-1 with goals from Timo Werner and Pape Matar Sarr as interim Manchester United ( MANU ) manager Ruud van Nistlerooy led his side to a thumping 5-2 win over Leicester City in the League Cup fourth round on Wednesday.

Former United striker Van Nistelrooy's victory in his first game in charge brought much-needed cheer to Old Trafford after the sacking of Erik ten Hag and a miserable run in the Premier League.

"I am here to help, to serve and give my everything for the club, that will never change," Van Nistelrooy said after his interim stint got off to an electrifying start with midfielders Bruno Fernandes and Casemiro scoring twice each.

Spurs manager Ange Postecoglou remains in with a chance of fulfilling his promise to win a trophy in his second season as coach of the North London club after a superb attacking display.

City made seven changes form the side that beat Southampton 1-0 at the weekend and they were opened up early as Spurs quickly played through their press. Dejan Kulusevski picked out Werner in the box, and the German striker lashed the ball into the net for his first goal of the season.

Sarr got the second in the 25th minute after the ball found its way to him outside the penalty area following a well-worked corner, and the Senegalese midfielder curled it brilliantly inside the right-hand post.

City pulled one back in first-half stoppage time as Matheus Nunes connected with a cross from Savinho to score with their first effort on target.

ANOTHER CITY INJURY

Having already lost key players this season, City coach Pep Guardiola said he wanted his side to perform well with no injuries, but Savinho picked up a knock that saw him carried off in the 62nd minute.

That robbed City of momentum, but Nico O'Reilly still almost grabbed a late equaliser, only for substitute Yves Bissouma to clear the ball off the line as Spurs hung on for victory.

"It's a cup tie played against a formidable opponent, I thought we did well for the most part," Postecoglou told Sky Sports.

"We didn't allow too many clearcut chances, we could have put the game away but City are always going to push you," he added.

Cody Gakpo struck twice for Liverpool as they beat Brighton & Hove Albion 3-2 and Arsenal enjoyed a comfortable 3-0 win at Preston North End to book their spot in the last eight by knocking out the last non-Premier League club left in the competition.

Crystal Palace grabbed a 2-1 win at Aston Villa, while an Alexander Isak strike and an own goal from Axel Disasi helped Newcastle United ease to a 2-0 home win over Chelsea to make it through to the last eight.

Tottenham will host Manchester United ( MANU ) in the quarter-finals, Arsenal face Crystal Palace, Newcastle play Brentford and Liverpool travel to Southampton.