01:55 PM EDT, 04/12/2024 (MT Newswires) -- PaxMedica ( PXMD ) shares surged after the company said late Thursday it reached an "important milestone" to enable a new drug application submission and for potential commercial availability in the US of suramin to treat a fatal tropical disease known as Stage 1 Human African Trypanosomiasis.

Shares more than doubled as intraday trading volume soared to over 105.6 million from a daily average of about 241,000.

HNR Acquisition Corp. ( HNRA ) said it may be able to capture the potential untapped oil in the Grayburg and San Andres oil zones in the "near term."

Shares soared 40% as intraday trading volume shot to more than 1.92 million from a daily average of about 348,000.

NextPlat ( NXPL ) shares surged 25% amid heavy trading after the company said Friday it signed a definitive business combination agreement with Progressive Care, its majority-owned subsidiary.

More than 42.8 million shares traded intraday compared with a daily average of almost 13,000.

Price: 0.83, Change: +0.42, Percent Change: +100.72