08:15 AM EDT, 11/01/2024 (MT Newswires) -- ESSA Pharma ( EPIX ) shares plunged 70% in recent Friday premarket activity, a day after saying it planned to terminate a phase 2 clinical study evaluating the combination of masofaniten and enzalutamide in patients with metastatic castration-resistant prostate cancer compared with enzalutamide.

Lexicon Pharmaceuticals ( LXRX ) stock tumbled 37%, after saying late Thursday that the US Food and Drug Administration's Endocrinologic and Metabolic Drugs Advisory Committee said the company's Zynquista inhibitor's benefits do not "outweigh" the risks in adults having type 1 diabetes and chronic kidney disease.

DigitalBridge Group ( DBRG/PJ ) shares were down 6% after it reported lower Q3 distributable earnings and total revenue compared with a year earlier.

Telephone and Data Systems ( TDS/PV ) stock slipped nearly 6% after it reported a wider Q3 net loss and lower revenue compared with last year.