07:33 AM EST, 03/07/2025 (MT Newswires) -- Plus Therapeutics ( PSTV ) shares were up 40% pre-bell Friday, extending Thursday's rally after the company said it secured the US Food and Drug Administration's orphan drug designation for Rhenium obisbemeda radiotherapy to treat leptomeningeal metastases in lung cancer patients.

Sotera Health ( SHC ) stock was 32% higher after a 1.9% gain in the previous session.

CuriosityStream ( CURI ) shares were up 31%, reversing from Thursday's losses.

Xencor ( XNCR ) shares were up 29% following a muted session.