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Top Premarket Gainers
Oct 7, 2025 5:20 AM

07:46 AM EDT, 10/07/2025 (MT Newswires) -- Trilogy Metals ( TMQ ) stock was up more than three-fold pre-bell Tuesday after the company said overnight that President Donald Trump has approved key federal permits for the Ambler Access Project in Alaska.

Zeta Network Group ( ZNB ) shares were 100% higher after the company said it formed a strategic collaboration with SOLV Foundation to advance cryptocurrency finance.

C3is ( CISS ) stock was up 46% after a 1.3% loss in the previous session.

Spruce Biosciences ( SPRB ) shares were 40% higher after the company said the US Food and Drug Administration granted a breakthrough therapy designation for tralesinidase alfa in Sanfilippo syndrome.

Lexeo Therapeutics ( LXEO ) stock was up 33% after the company said the US Food and Drug Administration has indicated openness to a biologics license application submission for accelerated approval of the company's Friedreich ataxia cardiomyopathy treatment candidate.

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