LONDON, Sept 4 (Reuters) - Britain's health regulator
said on Wednesday that the available data does not establish a
link between a popular class of diabetes and obesity drugs,
including Novo Nordisk's Wegovy, and suicidal
thoughts.
The Medicines and Healthcare products Regulatory Agency
(MHRA) began a review of safety data for the class of drugs,
known as GLP-1 receptor agonists, more than a year ago after
some patients reported suicidal or self-harming thoughts.
"We conclude that the available data does not support a
causal association between GLP-1 receptor agonists and suicide,
suicidal ideation, self-injury and depression, and therefore no
updates to the product information is warranted at this time,"
it said in a statement.
The UK review began weeks after similar action by the
European Union. It included Wegovy and another Novo Nordisk
drug, Ozempic, which contains the active ingredient semaglutide
and is approved to treat Type 2 diabetes.
The EU drug regulator said in April that its own review had
found no evidence that the class of medicines are linked to
suicidal thoughts.
The U.S. Food and Drug Administration said in January that
its preliminary review had not found evidence that GLP-1 drugs
were linked to suicidal thoughts, but that it will continue to
study the issue.