08:14 AM EST, 11/05/2025 (MT Newswires) -- The broad market exchange-traded fund SPDR S&P 500 ETF Trust ( SPY ) was down 0.2% and the actively traded Invesco QQQ Trust (QQQ) was 0.3% lower in Wednesday's premarket activity, ahead of the ADP jobs report.

US stock futures were mixed, with S&P 500 Index futures down 0.1%, Dow Jones Industrial Average futures gaining 0.02%, and Nasdaq futures retreating 0.2% before the start of regular trading.

US mortgage applications declined 1.9% in the week ended Oct. 31 after a sharp rise the prior week, as slightly higher rates led to a 3% drop in refinancing and a 1% decrease in purchase activity, Mortgage Bankers Association data showed Wednesday.

The private-sector October ADP Employment Report is slated for an 8:15 am ET release.

The S&P Global October composite purchasing manager index report will be released at 9:45 am ET, followed by the October ISM services index report at 10 am ET.

The weekly EIA petroleum status bulletin posts at 10:30 am ET.

In premarket activity, bitcoin was up by 1.7%. Among cryptocurrency ETFs, the cryptocurrency fund ProShares Bitcoin Strategy ETF (BITO) was 1.8% higher, Ether ETF (EETH) rose by 4.4%, and Bitcoin & Ether Market Cap Weight ETF (BETH) gained marginally by 0.03%.

Power Play:

Financial

Financial Select Sector SPDR Fund (XLF) advanced 0.04%. Direxion Daily Financial Bull 3X Shares ( FAS ) was up 0.2%, while its bearish counterpart Direxion Daily Financial Bear 3X Shares ( FAZ ) was 0.1% lower.

Upstart Holdings ( UPST ) shares were down more than 13% pre-bell after the company cut its 2025 revenue forecast.

Winners and Losers:

Health Care

The Health Care Select Sector SPDR Fund ( XLV ) advanced 0.2%. The Vanguard Health Care Index Fund ( VHT ) gained 0.1%, while the iShares US Healthcare ETF ( IYH ) was inactive. The iShares Biotechnology ETF (IBB) was up 0.1%.

Guardant Health ( GH ) stock was down more than 7% premarket after the company said it priced an upsized public offering of 3.3 million shares at $90 apiece for estimated net proceeds of $284.4 million.

Technology

Technology Select Sector SPDR Fund (XLK) retreated 0.5%, and the iShares US Technology ETF ( IYW ) was 0.5% lower, while the iShares Expanded Tech Sector ETF ( IGM ) was down 1.1%. Among semiconductor ETFs, SPDR S&P Semiconductor ETF (XSD) was flat, while the iShares Semiconductor ETF (SOXX) declined by 0.3%.

Qualys ( QLYS ) shares were up more than 4% in recent premarket activity after the company reported higher Q3 non-GAAP net income and revenue.

Industrial

Industrial Select Sector SPDR Fund ( XLI ) retreated 0.2% while the Vanguard Industrials Index Fund ( VIS ) and the iShares US Industrials ETF ( IYJ ) were inactive.

Kratos Defense & Security Solutions (KTOS) stock was down more than 5% before the opening bell as the company's fiscal Q4 revenue forecast came in below the expectations of analysts surveyed by FactSet. Kratos also announced a $356.3 million deal to acquire Orbit Technologies.

Consumer

The Consumer Staples Select Sector SPDR Fund ( XLP ) retreated by 0.01%, while the Vanguard Consumer Staples Fund (VDC) was up 0.4%. The iShares US Consumer Staples ETF ( IYK ) was inactive, while the Consumer Discretionary Select Sector SPDR Fund ( XLY ) advanced 0.4%. The VanEck Retail ETF ( RTH ) was inactive, while the SPDR S&P Retail ETF (XRT) was down 0.1%.

Toyota Motor ( TM ) shares were down more than 2% pre-bell after the company said it expects US tariffs to have a 1.45 trillion yen negative impact on its fiscal 2026 operating income.

Energy

The iShares US Energy ETF ( IYE ) was inactive, while the Energy Select Sector SPDR Fund ( XLE ) was up by 0.1%.

Cameco ( CCJ ) stock was down more than 2% before Wednesday's opening bell after the company reported lower Q3 revenue.

Commodities

Front-month US West Texas Intermediate crude oil retreated 0.4% to $60.35 per barrel on the New York Mercantile Exchange. Natural gas was down 2% at $4.26 per 1 million British Thermal Units. The United States Oil Fund ( USO ) declined by 0.01%, while the United States Natural Gas Fund ( UNG ) was nearly 1% lower.

Gold futures for December gained by 0.3% to reach $3,973.50 an ounce on the Comex, while silver futures declined by 0.02% to $47.27 an ounce. SPDR Gold Shares ( GLD ) was up by 0.7%, and the iShares Silver Trust ( SLV ) was 0.9% higher.