Major U.S. indices ended mixed on Wednesday, with the Dow Jones Industrial Average slipping 0.04% to 46,253.31. The S&P 500 added 0.4% to 6,671.06, while the Nasdaq climbed nearly 0.7% to 22,670.08.

These are the top stocks that gained the attention of retail traders and investors through the day:

Hims & Hers Health Inc ( HIMS ) 

Hims & Hers Health ( HIMS ) shares surged 16.18%, closing at $62.76. The stock reached an intraday high of $65.30 and a low of $54.44, with a 52-week range of $18.32 to $72.98.

The rise follows the company’s announcement of a new menopause and perimenopause care specialty on its Hers platform, offering personalized treatment plans.

Salesforce Inc ( CRM ) 

Salesforce ( CRM ) shares fell 1.33%, ending at $236.58. The stock fluctuated between $241.32 and $235.90 during the day, with a 52-week range of $226.48 to $369. In the after-hours trading, the stock rose almost 3.6% to $245.

Salesforce ( CRM ) shares have drawn attention this week following the company's announcement of a new partnership with OpenAI. The tech giant unveiled several major AI collaborations, fueling investor interest. As part of the expanded strategic alliance, Salesforce ( CRM ) plans to integrate its Agentforce 360 platform with OpenAI's cutting-edge models to enhance both employee productivity and customer experiences.

Omeros Corporation ( OMER ) 

Omeros ( OMER ) stock skyrocketed 154.15%, closing at $10.42. The stock hit an intraday high of $12.10 and a low of $9.19, with a 52-week range of $2.95 to $13.60. The dramatic increase followed a $2.1 billion deal with Novo Nordisk for the development and commercialization of a rare disease drug.

United Airlines Holdings ( UAL ) 

United Airlines shares rose 0.87%, closing at $104.05. The stock traded between $104.53 and $102.73, with a 52-week range of $52 to $116.

The airline’s stock gained traction after reporting better-than-expected third-quarter earnings and a positive fourth-quarter outlook, driven by strong customer loyalty. For the quarter, adjusted earnings per share were reported at $2.90. The company issued guidance for diluted earnings per share in the range of $3.00 to $3.50.

Sea Limited ( SE ) 

Sea Limited ( SE ) shares dropped 9.56%, finishing at $163.42. The stock’s intraday high was $184.96, with a low of $162.02, and a 52-week range of $92.50 to $199.30. In the after-hours trading, the stock rose 2.2% to $167.

Sea Ltd. ( SE ) recently released its second-quarter earnings, which indicated that revenue increased 38.2% year-over-year to $5.26 billion, surpassing the analyst consensus estimate of $4.98 billion.

Benzinga’s Edge Stock Rankings indicate Hims & Hers has a Value in the 7th percentile. Here is how the stock ranks on other metrics.

Prepare for the day’s trading with top premarket movers and news by Benzinga.

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This story was generated using Benzinga Neuro and edited by Shivdeep Dhaliwal