09:17 AM EDT, 08/14/2025 (MT Newswires) -- Health care stocks were declining premarket Thursday, with The Health Care Select Sector SPDR Fund ( XLV ) 0.2% lower and the iShares Biotechnology ETF (IBB) down 0.7%.

Schrodinger (SDGR) stock was down more than 13% after the company said it has discontinued its program for SGR-2921, which was intended to treat relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.

Beam Therapeutics ( BEAM ) shares were up more than 5% after the company said the US Food and Drug Administration has granted regenerative medicine advanced therapy designation to BEAM-101, an investigational genetically modified cell therapy for the treatment of sickle cell disease.

Sarepta Therapeutics ( SRPT ) said it has sold about 9.3 million common shares of Arrowhead Pharmaceuticals ( ARWR ) for at least $174 million in gross proceeds. Shares of Arrowhead Pharmaceuticals ( ARWR ) were down nearly 6% premarket.