09:16 AM EDT, 08/21/2025 (MT Newswires) -- Health care stocks were falling premarket Thursday, with the Health Care Select Sector SPDR Fund ( XLV ) 0.3% lower and the iShares Biotechnology ETF (IBB) down 0.2%.

Ascentage Pharma Group International ( AAPG ) shares were down more than 2% after the company reported that it swung to an H1 loss as revenue declined during the period.

Novavax ( NVAX ) stock was nearly 7% lower after the company said it has entered agreements with some of the holders of its existing 5% convertible senior notes due 2027 and new investors, under which the company will issue $225 million worth of 4.625% convertible senior notes due 2031.

Sarepta Therapeutics ( SRPT ) shares were down more than 6% after the company announced separate exchange agreements with certain holders of its convertible senior notes.