09:19 AM EDT, 10/23/2025 (MT Newswires) -- Health care stocks were mixed pre-bell Thursday, with The Health Care Select Sector SPDR Fund ( XLV ) declining by 0.3% and the iShares Biotechnology ETF (IBB) up 0.6%.

West Pharmaceutical Services ( WST ) stock was up more than 7% after the company posted higher Q3 non-GAAP earnings and net sales in addition to raising its 2025 guidance.

Moderna ( MRNA ) shares were down more than 4% after the company said a phase 3 trial of mRNA-1647 investigational vaccine failed to meet its primary efficacy endpoint of preventing cytomegalovirus infection in seronegative women of childbearing age between 16 to 40 years.

Harmony Biosciences ( HRMY ) shares were up more than 5% after the company raised its 2025 revenue guidance.