09:19 AM EDT, 09/03/2025 (MT Newswires) -- Health care stocks were mixed pre-bell Wednesday, with the iShares Biotechnology ETF (IBB) up 0.4% and the Health Care Select Sector SPDR Fund ( XLV ) 0.3% lower.

Precigen ( PGEN ) shares were up more than 2% after the company said it has signed a two-tranche credit facility deal of up to $125 million with investment funds managed by Pharmakon Advisors.

TG Therapeutics ( TGTX ) stock was up more than 1% after the company said its board approved a new share repurchase program of up to $100 million.

Achieve Life Sciences ( ACHV ) shares were up more than 3% after the company said the US Food and Drug Administration has accepted its marketing application for cytisinicline, a new treatment to help adults quit smoking.