08:15 AM EDT, 09/03/2024 (MT Newswires) -- US stock futures are heading lower in Tuesday's premarket session as markets reopen after Monday's Labor Day holiday and as investors await manufacturing data set for release later in the morning.

Dow Jones Industrial Average futures were down 0.52%, S&P 500 futures were declining 0.55%, and Nasdaq futures were moving 0.71% lower.

Investors will be looking ahead today to the manufacturing Purchasing Managers Index reading for August, which is expected to decline to 48.0 from 49.6 in July, according to Bloomberg.

The Institute for Supply Management's manufacturing index reading for August will also be announced later in the morning. Forecasters are expecting the score to rise to 47.5 from 46.8 in July, according to Bloomberg.

Oil prices were moving sharply lower, with front-month global benchmarks Brent crude and West Texas Intermediate dropping 2.14% and 1.43% respectively.

In equities, Sify Technologies ( SIFY ) shares surged 164% in recent Tuesday premarket activity, after it said Monday that it has been certified to offer liquid cooling technology for Nvidia ( NVDA ) data centers. Vaxcyte's ( PCVX ) shares jumped 36% after it reported positive topline results Tuesday from a phase 1/2 study evaluating VAX-31 to prevent invasive pneumococcal disease. And shares of Aptose Biosciences ( APTO ) advanced 31% after it said Friday that it received a $10 million loan under a facility agreement with Hanmi Pharmaceutical.

On the losing side, shares of Dyne Therapeutics (DYN) plunged 33%, following a 1.8% gain on Friday. Agape ATP's ( ATPC ) stock tumbled 15%, paring gains from Friday when the stock surged 60%, and shares of Quantum BioPharma ( QNTM ) dropped 14%, adding to a more than 8% loss on Friday.