07:29 AM EDT, 05/14/2025 (MT Newswires) -- The main US stock measures edged up in Wednesday's premarket activity as investors digest the latest consumer price inflation report, while President Donald Trump again called on the Federal Reserve to lower interest rates.

The S&P 500 and the Dow Jones Industrial Average were slightly in the green before the opening bell, while the Nasdaq increased 0.1%. The S&P 500 and the Nasdaq finished the previous trading session higher, while the Dow closed in the red.

Government data on Tuesday showed that consumer prices in the world's largest economy rebounded last month, but missed Wall Street's estimates, while annual inflation eased to the lowest level since February 2021. "There isn't a lot of evidence of tariffs boosting the (consumer price index) in April, but this shouldn't be surprising as it takes time," Oxford Economics said Tuesday in remarks emailed to MT Newswires.

The US and China recently reached an agreement on a 90-day suspension of reciprocal duties. The two countries had been in a trade war since Trump's announcement of sweeping new tariffs early last month.

The producer price index and the retail sales report, both for April, are out on Thursday. Wednesday's economic calendar has the weekly mortgage applications bulletin at 7 am ET, followed by the weekly EIA domestic petroleum inventories report.

In a social media post late Tuesday, Trump repeated his call for the Fed to cut interest rates, saying there was no inflation and prices of gas, energy and groceries are down. Last week, the Fed kept its benchmark lending rate unchanged and warned that upside risks to inflation and unemployment have increased.

Fed Vice Chair Philip Jefferson is scheduled to speak at 9:10 am, while San Francisco Fed President Mary Daly speaks at 5:40 pm.

US Treasury yields fell in premarket action, with the two-year rate retreating 2.1 basis points to nearly 4% and the 10-year rate declining 4.2 basis points to 4.46%.

Shares of Nvidia ( NVDA ) were up 1.8% pre-bell as the tech bellwether announced a partnership with Humain, an artificial intelligence company backed by Saudi Arabia's Public Investment Fund. Amazon.com ( AMZN ) , Alphabet's (GOOG, GOOGL) Google ( GOOG ), and Advanced Micro Devices ( AMD ) also disclosed separate partnerships with the firm.

The collaboration could open up a "huge opportunity" and total addressable market for Nvidia ( NVDA ), Palantir Technologies ( PLTR ) , Microsoft ( MSFT ) , Amazon ( AMZN ), Alphabet, Tesla (TSLA), and other "well-positioned" chip and software companies over the coming years, Wedbush Securities said in a Wednesday client note.

UnitedHealth Group ( UNH ) rebounded 2.6% in premarket activity after closing the previous trading session down 18%. American Eagle Outfitters ( AEO ) slid 14% as the clothing retailer withdrew its fiscal 2025 outlook and forecast an operating loss for its first quarter.

Cisco Systems ( CSCO ) is among the companies reporting its latest financial results after the markets close.

West Texas Intermediate crude oil decreased 1.1% to $62.99 a barrel before the opening bell. Bitcoin moved 0.9% lower to $103,812, while gold nudged down 0.3% to $3,237 per troy ounce.