Jan 7 (Reuters) - Biotech firm Maze Therapeutics, backed
by Third Rock Ventures, revealed a profit for the first nine
months of 2024 in its paperwork for a U.S. initial public
offering (IPO) filing on Tuesday.
The U.S. IPO market has seen an uptick amid falling interest
rates, strong equity markets, and hopes of a friendlier
regulatory environment under the incoming Trump administration.
Maze's decision follows a strong 2024 for biotech companies,
with firms such as Septerna ( SEPN ) and Bicara Therapeutics ( BCAX )
receiving a positive response from investors at their
debut.
Maze said it earned $9.03 million for the nine months ended
Sept. 30, 2024, compared with a loss of $73.84 million in the
year-ago period.
The terms of the IPO were not disclosed in the offering.
The San Francisco, California-based company is also backed
by healthcare investors ARCH Venture Partners and General
Catalyst.
Maze is advancing two fully-owned lead programs, MZE829 and
MZE782, both of which represent a "novel precision
medicine-based" approach for chronic kidney disease.
The funds raised from the IPO will be used to advance the
clinical development of these lead programs.
The company is also developing another program, MZE001, for
a genetic disorder called Pompe disease through a partnership
agreement with Japanese firm Shionogi.
France-based healthcare company Sanofi had
previously announced a global licensing agreement with Maze for
MZE001 in May 2023.
However, Sanofi later scrapped the agreement following an
administrative complaint issued by the Federal Trade Commission,
which cited the French firm's monopoly in the treatment of Pompe
disease.
Maze Therapeutics intends to list its shares on the Nasdaq
Global Market under the ticker symbol "MAZE".
J.P. Morgan, TD Cowen, Leerink Partners and Guggenheim
Securities are the lead underwriters of the offering.