01:51 PM EDT, 10/21/2025 (MT Newswires) -- Neuphoria Therapeutics ( NEUP ) said Monday that a phase 3 trial of BNC210 for the acute treatment of social anxiety disorder failed to meet its primary endpoint.

Shares sank 66% following an increase in intraday trading volume to over 2.2 million from a daily average of about 81,000.

Newmont ( NEM ) shares dropped 9.3% along with declines in gold and silver mining peers amid a sharp sell-off in precious metals from record highs.

More than 11.3 million shares of Newmont ( NEM ) traded intraday compared with a daily average of about 10.9 million.

Cleveland-Cliffs ( CLF ) shares dropped 18% after Wells Fargo downgraded the stock to underweight from equal weight with a price target of $11.

Intraday volume topped 45.9 million shares, compared with the daily average of almost 26 million.

Price: 86.08, Change: -8.81, Percent Change: -9.28