12:43 PM EDT, 09/24/2025 (MT Newswires) -- uniQure (QURE) reported Wednesday positive topline results from its pivotal phase I/II study of AMT-130 in patients with Huntington's disease.

The stock was up over 259% after midday Wednesday, with trading volume of about 50.2 million shares against a daily average of more than 1.1 million.

SHF Holdings ( SHFS ) shares rose nearly 110% after midday trading on Wednesday, following the company's announcement in a Form 8-K filing that it has reached a stock purchase agreement with CREO Investments.

Trading volume exceeded 27.9 million shares against a daily average of over 851,000.

Lithium Americas ( LAC ) said Wednesday it is in talks with the US Department of Energy and General Motors ( GM ) regarding its Thacker Pass lithium joint venture, including a pending $2.26 billion financing.

The company's shares were up roughly 95% while trading volume crossed 236.6 million against an average of about 8.8 million.

Price: 49.15, Change: +35.49, Percent Change: +259.81