April 29 (Reuters) - Wall Street's main indexes were

mixed at the open on Wednesday as investors treaded carefully

ahead of several Big Tech earnings reports and a Federal Reserve

meeting expected to be the last for Jerome Powell as its Chair.

The Dow Jones Industrial Average rose 21.8 points, or

0.04%, at the open to 49,163.78. The S&P 500 fell 7.2

points, or 0.10%, at the open to 7,131.61​, while the Nasdaq

Composite dropped 57.3 points, or 0.23%, to 24,606.527.

(Reporting by Niket Nishant and Utkarsh Hathi in Bengaluru;

Editing by Devika Syamnath and Arun Koyyur)