March 25 (Reuters) - Wall Street's main indexes opened

higher on Wednesday as prospects of a de-escalation in the

Middle East conflict allayed some investor fears around

prolonged energy supply disruptions.

The Dow Jones Industrial Average rose 190.2 points,

or 0.41%, at the open to 46,314.24. The S&P 500 rose 42.0

points, or 0.64%, at the open to 6,598.35​, while the Nasdaq

Composite rose 244.5 points, or 1.12%, to 22,006.428 at

the opening bell.

(Reporting by Purvi Agarwal in Bengaluru; Editing by Devika

Syamnath)