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Futures down: Dow 0.18%, S&P 500 0.43%, Nasdaq 0.62%

Nov 21 (Reuters) - Nasdaq futures led declines among

U.S. stock index futures on Thursday, with Nvidia's ( NVDA ) shares

falling in premarket trading after investors were unimpressed by

the AI leader's revenue forecast.

At 04:20 a.m. ET, Dow E-minis were down 80 points,

or 0.18%, S&P 500 E-minis were down 25.75 points, or

0.43%, and Nasdaq 100 E-minis were down 127.75 points,

or 0.62%.

Nvidia ( NVDA ) beat quarterly profit expectations, but the

company projected its slowest revenue growth in seven quarters

and its adjusted gross margins shrank, sending its shares down

3.8% in premarket trading.

"At face value, Nvidia ( NVDA ) has once again generated the kind of

growth that most companies will never achieve in their

lifespan," said Dan Coatsworth, investment analyst at AJ Bell.

"What's troubled investors this time was a

quarter-on-quarter decline in gross margins, with guidance for

them to fall further in the coming quarter and

weaker-than-expected forward guidance for revenue."

The sentiment spread to other chip stocks, with Broadcom ( AVGO )

down 1%, Qualcomm ( QCOM ) losing 1.1% and Advanced

Micro Devices ( AMD ) off 0.7%.

Growth stocks also dipped. Microsoft ( MSFT ) was down 0.3%,

while Apple ( AAPL ) and Amazon.com ( AMZN ) slipped 0.2% each.

Nvidia ( NVDA ) has led much of the U.S. market rally since mid-2023,

on expectations that artificial intelligence integration could

boost corporate profits. The stock has risen more than ninefold

in the past two years and the company boasts a market value of

$3.5 trillion.

Wall Street indexes have retreated from their record highs,

with post-election euphoria giving in to caution after

President-elect Donald Trump named his cabinet picks, as markets

weigh the potential inflationary impact of his policies.

Investors also kept an eye on escalating tensions between

Russia and Ukraine, after Russia launched an intercontinental

ballistic missile in retaliation against Ukraine's strike using

American and British missiles earlier this week.

On the data front, a weekly report on jobless claims is due

at 8.30 a.m. ET, while comments from Federal Reserve officials

Beth Hammack, Austan Goolsbee and Vice Chair for Supervision

Michael Barr are on tap.

Money market participants are pricing in a higher chance of

the Fed lowering interest rates by 25 basis points at its

December meeting - about 55.7%, according to the CME Group's

FedWatch.

Alphabet dropped 0.5% after the Justice Department

argued to a judge that Google must sell its Chrome browser and

take other measures to end its monopoly on online search.

Crypto stocks such as MARA Holdings ( MARA ) jumped 9.3%,

MicroStrategy ( MSTR ) soared 8.6% and Coinbase gained

2.9% as bitcoin prices soared to nearly $100,000 for the

first time.

Deere, Baidu and PDD Holdings ( PDD ) are

among companies set to report quarterly earnings before market

open.

Snowflake raised its annual product revenue

forecast and said it has teamed up with AI firm Anthropic to

build up its cloud services, sending the data analytics

provider's shares up 20%.

Palo Alto Networks ( PANW ) lost 5.3% after announcing a

two-for-one forward stock split after the cybersecurity firm

topped quarterly revenue and profit expectations.