(For a Reuters live blog on U.S., UK and European stock

markets, click or type LIVE/ in a news window.)

*

Indexes down: Dow 4.61%, S&P 500 5.45%, Nasdaq 6.48%

*

CarMax ( KMX ) falls as Q4 profit misses estimates

*

March CPI at 2.4% YoY vs 2.6% estimate

(Updates prices, adds comment)

By Shashwat Chauhan and Purvi Agarwal

April 10 (Reuters) -

Wall Street's main indexes tumbled on Thursday on concerns

over the impact of high U.S. tariffs on global economy, with

stocks pulling back sharply from the day-ago gains when

President Donald Trump moved to pause the levies on some

countries.

The

90-day halt in tariffs

had lifted the S&P 500 to its biggest single-day

percentage gain since 2008 on Wednesday. The Nasdaq

posted its biggest one-day jump since 2001.

Trump turned up the heat on China on Thursday, raising

the total levy on imports from the country to 145%, according to

a CNBC report, citing the White House. Beijing had slapped 84%

tariffs on U.S. imports.

"While yesterday seemed to be a significant rally in the

face of good news in terms of the potential for negotiations,

the bad news is the trade war with China continues to escalate,"

said Art Hogan, chief market strategist, B Riley Wealth.

Meanwhile, data showed the consumer price index unexpectedly

dipped 0.1% in March and advanced 2.4% in the 12 months through

March. Economists polled by Reuters had forecast the CPI edging

up 0.1% and climbing 2.6% year-on-year.

Fed Governor Michelle Bowman said it is unclear how the

tariffs might affect the economy.

Traders now see nearly 90 basis points of interest-rate cuts

in 2025, according to LSEG data.

At 12:19 p.m. ET, the Dow Jones Industrial Average

fell 1,872.86 points, or 4.61%, to 38,735.59, the S&P 500

lost 298.72 points, or 5.45%, to 5,158.18 and the Nasdaq

Composite lost 1,091.78 points, or 6.38%, to 16,033.20.

An auction of 30-year Treasury notes at 1:00 p.m. ET will be

in focus.

Most S&P 500 sectors nursed losses. Information technology

and energy led the fall, down more than 7%

each.

Big Tech came under pressure once again, with Apple ( AAPL )

down 7%, Microsoft ( MSFT ) 4.7% and Nvidia ( NVDA ) 8.5%.

"Any pullback today would be very normal after a really big

move like yesterday's. I would expect that for the next day or

two we could see some profit taking," said Larry Tentarelli,

chief technical strategist at Blue Chip Daily Trend Report.

Despite Wednesday's bounce, the S&P 500 and the Dow

are more than 8% below levels seen before the reciprocal tariffs

were announced last week.

CarMax ( KMX ) slid 20.2% after the used-car retailer missed

fourth-quarter profit expectations.

U.S. earnings season could also offer more insights into the

health of corporate America. Big banks such as JPMorgan Chase ( JPM )

will report first-quarter results on Friday.

Declining issues outnumbered advancers by a 7.15-to-1 ratio

on the NYSE and by a 4.85-to-1 ratio on the Nasdaq.

The S&P 500 posted no new 52-week highs and three new lows

while the Nasdaq Composite recorded nine new highs and 84 new

lows.

(Reporting by Shashwat Chauhan and Purvi Agarwal in Bengaluru;

Editing by Arun Koyyur)