* Futures: Nasdaq up 0.27%, Dow down 0.07%, S&P 500 flat

* Data-storage stocks gain after Seagate's ( STX ) upbeat

forecast

* Starbucks ( SBUX ) up after lifting forecast

(Updates before market open)

By Niket Nishant and Utkarsh Hathi

April 29 (Reuters) - Wall Street futures pointed to a

mixed open for the indexes on Wednesday as investors treaded

carefully ahead of several Big Tech earnings reports and a

Federal Reserve meeting expected to be the last for Jerome

Powell as its Chair.

Amazon ( AMZN ), Meta Platforms ( META ), Microsoft ( MSFT )

and Google-parent Alphabet are set to report after the

closing bell, when investors will gauge how their AI bets are

paying off.

The results could shape investor confidence in one of the

most resilient pockets of the financial markets, after sentiment

was slightly dampened following a Wall Street Journal report

that said OpenAI had missed its internal targets for weekly

users and revenue, reviving fears about the AI spending spree of

tech heavyweights.

"Tech has had an impressive rebound so far this quarter. The

question now is whether mega-cap tech can help push this rally

to new heights," said Bret Kenwell, U.S. investment analyst at

eToro.

"Semiconductors have done much of the heavy lifting. There's

clearly powerful momentum behind the group, but even the

strongest rallies need time to reset."

The Philadelphia SE Semiconductor Index has gained

41.7% so far this year.

Amazon ( AMZN ), Meta, Alphabet and Microsoft ( MSFT ) slipped between 0.3%

and 0.5% in premarket trading.

At 8:43 a.m. ET, Nasdaq 100 E-minis gained

73.5 points, or 0.27%, S&P 500 E-minis slipped

1.25 points, or 0.02%, and Dow E-minis fell 36 points,

or 0.07%.

POWELL'S CURTAIN CALL?

Investors will also tune in to Fed Chair Jerome Powell's

final press conference as the head of the U.S. central bank.

Republican Senator Thom Tillis dropped his objection to the

Senate confirmation of ​Kevin Warsh, whom President Donald Trump

had nominated to succeed Powell, after the Department of

​Justice ended ​an investigation ⁠into Powell that Tillis felt

was a threat ​to the Fed's independence.

Traders expect the central bank to leave rates unchanged,

but will closely parse Powell's remarks.

The Fed has said it was monitoring risks tied to the

conflict, and with tensions in the Middle East showing few signs

of easing, some investors worry policymakers may have to factor

them more heavily into their outlook.

"While Powell's signals may be taken with some caution,

given that this should be his last press conference, the risks

are that he errs on the hawkish side," wrote ING Economics' FX

strategist Francesco Pesole.

Iran's latest proposal for ending the two-month war would

set aside discussion of its nuclear program until the conflict

was concluded and shipping disputes resolved. Trump, however,

said he was unhappy with the offer.

Meanwhile, major movers in the premarket session include

online brokerage Robinhood Markets ( HOOD ), which fell 11.6%

after missing expectations for first-quarter profit.

Shares of data-storage companies climbed following an upbeat

fourth-quarter forecast from Seagate Technology ( STX ). Seagate ( STX )

jumped 15.9%, while peers Micron Technology ( MU ), Sandisk ( SNDK )

and Western Digital ( WDC ) gained 4.8%, 6.4%, and

9.7%, respectively.

Coffee giant Starbucks ( SBUX ) rose 4.3% after raising its

annual profit forecast.

Payments-processing firms Visa and Mastercard ( MA )

added 5.6% and 2.6%, respectively, after Visa raised its

forecast for full-year earnings.

NXP Semiconductors ( NXPI ) rose 21.2% after it said it

expects second-quarter revenue and profit above Wall Street

expectations.

(Reporting by Niket Nishant and Utkarsh Hathi in Bengaluru;

Editing by Devika Syamnath and Arun Koyyur)