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Indexes up: Dow 0.60%, S&P 500 1.22%, Nasdaq 1.96%

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Metsera ( MTSR ) slumps after Pfizer wins bidding war

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Health insurers fall after Trump's comments on healthcare

funds

(Updates after markets open)

By Twesha Dikshit and Purvi Agarwal

Nov 10 (Reuters) - Wall Street's main indexes gained on

Monday, following signs of progress in Washington to end a

record government shutdown that has stalled economic data

releases and intensified concerns over the state of the economy.

On Sunday, senators advanced a House-passed bill in a

procedural vote that will be amended to fund the government

until January 30. If passed in the Senate, it would require

House approval and President Donald Trump's signature, which

could take several days.

"If we do get an end of the shutdown, it would be a

near-term positive ... with positioning cleaner, we could see

some dip buying," said Mohit Kumar, an economist at Jefferies.

"It would also open the path for data releases ... we should

start seeing initial claims data and there should be sufficient

time to collect data for the employment report in early

December."

Most tech stocks jumped, with Nvidia ( NVDA ) gaining 3.4%,

while Alphabet and Amazon.com ( AMZN ) added 3% each.

Information technology and consumer discretionary

stocks were the biggest boosts to the S&P 500 index.

At 09:44 a.m. ET, the Dow Jones Industrial Average

rose 283.95 points, or 0.60%, to 47,271.05, the S&P 500

gained 81.91 points, or 1.22%, to 6,810.71 and the Nasdaq

Composite gained 451.61 points, or 1.96%, to 23,456.15.

The CBOE Volatility Index eased 1.12 points to 17.96,

retreating from a three-week high touched on Friday.

The small-cap Russell 2000 gained 1.4%, while a

broader semiconductor index rose 3.1%.

Airlines, which have been facing disruption and

government-mandated cuts due to air traffic control staffing

shortages, rose on hopes the shutdown would end, with United

Airlines and Delta Airlines adding 2.5% each.

White House economic adviser Kevin Hassett said in an

interview that fourth-quarter U.S. economic growth could be

negative if the closure continues.

On betting website Polymarket, predictions for an end to the

shutdown this week stood at 85%.

The longest federal shutdown in history has created a data

gap for the Federal Reserve and markets alike, leaving them

dependent on private data that has given a mixed picture of the

economy.

Optimism around artificial intelligence has fueled a bull

run in U.S. stocks this year, but concerns around monetization

and circular spending within the sector drove a bout of selling

in tech stocks last week. The Nasdaq marked its worst

performance in over seven months.

Meanwhile, the third-quarter earnings season approached its

conclusion. Of the 446 S&P 500 companies that have reported, 83%

have delivered better-than-expected earnings, according to data

compiled by LSEG.

Venture Global ( VG ) jumped 10% after the LNG exporter

swung to a profit in the third quarter.

Shares of health insurers dropped after the U.S. Senate

struck a deal to end the 40-day federal shutdown without

extending Affordable Care Act subsidies, setting up a December

vote on the issue instead.

Centene ( CNC ) fell 9.5% to the bottom of the S&P 500,

while Humana and Elevance Health ( ELV ) lost 2% each.

Metsera ( MTSR ) slumped 15.6% after Pfizer won a $10

billion bidding war to acquire the company.

Advancing issues outnumbered decliners by a 2.44-to-1 ratio

on the NYSE and by a 2.84-to-1 ratio on the Nasdaq.

The S&P 500 posted 15 new 52-week highs and 3 new lows while

the Nasdaq Composite recorded 57 new highs and 45 new lows.